A Bezoar is a mass trapped in the stomach comprising some indigestible substance ingested by the human or animal. A traditional folk medicine in Malaysia: porcupine bezoar Authors (first, second and last of 4) Chu Shan Tan; Chiew Hoong Ng; Mun Fei Yam; Content type: Review; Published: 28 March 2019; Pages: 131 - 136 Azir Salleh, 1 No. Genuine Porcupine bezoar is a medically potent and rare animal gall stone that is commonly found in the stomach region of a porcupine. known as porcupine bezoar, a phytobezoar that is formed from the partly digested plant materials or herbs in the stomach of Himalayan porc( Hystrix brachyura )[8, RIDHWAN ABDUL WAHAB, Initially PB was infused in water for 18 h to get PB aqueous extract which was preliminary tested for total phenolic content (TPC), total flavonoid content (TFC), DPPH activity in order to confirm the presence of bioactive agents as antioxidants in PB. Porcupine bezoar (PB) has been previously reported to possess various medicinal properties. Pharm Hist (Lond) 43(1):13–22, Endangered animals of the world (2006) Animal info—Malaysia. Al’aina Yuhainis Firus Khan, Learn more about Institutional subscriptions, Bao SH (2014) 重镇化痰可治瘟病-箭猪枣非治百病. Pharmacogn Res 9(4):366–371, Article PubMed Hence, the present study was performed to study PB aqueous extracts (PBAE) in vivo toxicity effects using the zebrafish embryo model. One of the traditional folk medicine in the Malaysia is using porcupine bezoar. Tan, C.S., Ng, C.H., Loh, Y.C. Immediate online access to all issues from 2019. Hence, in this study, porcupine bezoar (PB) aqueous extract was evaluated for … Porcupine Bezoar Medical Value According to Chinese medicine records, our ancestors and some aborigines have knowledge on the medicinal values of the porcupine bezoar. However, its potential as an anticancer agent against human cancers is still poorly studied and understood. - 128.199.74.47. ANTI-PROLIFERATIVE PROPERTY OF PORCUPINE BEZOAR EXTRACT ON MELANOMA (A375). Adv Biotechnol Microbiol 5(1):555651, Lim AX (2015) 60% Artificial Porcupine Bezoar (豪猪枣60%仿冒). 3 No. Suppliyer porcupine stone / porcupine bezoar. Retrieved from http://www.orientaldaily.com.my/s/74980, Liu XH (2016) The mystery of porcupine bezoar (箭猪枣之迷思). 1 No. A lifetime of grasses, herbs, bark, and other vegetation can leave little bits of indigestible matter behind in a porcupine’s digestive tract, where they occasionally congeal into a hard ball called a bezoar. Habibah Hassan, It is a molecular biology technique in order to create pores through a cell wall membrane, boost the permeability of the cell membrane, and support chemicals, drugs or DNA to be imported into Hela cells. As the Porcupine Bezoar is believed to have medicinal value is very high to the extent that it is called the king of herbs. The widespread use of the bezoar as an alternative medicine for treatment of deadly illnesses in Malaysia was passed down from generations of the multi-diverse ethnicity environment that existed here. Tara Jalal, Alaina Yuhanis Firus Khan, This quick miracle cure is also perceived to cure cancer, epilepsy, and typhoid.This preternatural or morbid concretions formed in the bodies of porcupines are composed of several layers that look like an onion. Porcupine date is a rare "stone" that found in the stomach of a porcupine. A pseudobezoar is an indigestible object introduced intentionally into the digestive system.. Porcupine bezoar (PB) is used in traditional medicine for various medical conditions. Google Scholar, Wong LP, AbuBakar S (2013) Health beliefs and practices related to dengue fever: a focus group study. Hence, in this study, porcupine bezoar (PB) aqueous extract was evaluated for … Alfi Khatib, However, limited scientific study has been carried out to verify these traditional claims. Abstract. CAS Genuine Porcupine Bezoar Date. Qamar Uddin Ahmed, Porcupine Bezoar Extract (PBE) has been previously described to possess diverse medicinal properties. The materials were collected by Loh Yean Chun. Tara Jalal, Springer, Singapore, pp 19–39, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Minden, Pulau Pinang, Malaysia, Chu Shan Tan, Chiew Hoong Ng, Yean Chun Loh & Mun Fei Yam, You can also search for this author in Arch Pathol Lab Med 104:159–161, CAS © 2020 Springer Nature Switzerland AG. Porcupine bezoars (PBs) are masses of undigested calcareous concretions formed within the gastrointestinal tract. Later I found out that bezoar is a mass of food, usually from consuming grass and herbs, found trapped in an animal’s stomach system and is historically used in Chinese traditional medicine. PubMed In … Contact Mr.Syaiful +6281389891852 , +601116377848 Porcupine Bezoar Medicinal Values According to Chinese medicine records, in tradition, Porcupine Bezoar had been used as medicine by hill tribes in Southern China and South-East Asia. 1 (2017): Special Issue: Enhancing Academic and Research Quality, CYTOTOXICITY OF LEUKEMIC CELLS BY NYPA FRUTICANS THROUGH REGULATION OF ADIPONECTIN EXPRESSION, INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES: Vol. Qamar Uddin Ahmed, Retrieved from http://www.animalinfo.org/country/malaysia.html, Holloway WD, Lee SP, Nicholson GI (1980) The composition and dissolution of phytobezoars. Ridzwan Hashim, Part of Springer Nature. This bezoar has been a myth to the locals. Samsul Draman, 2. PB aqueous extract showed significant anti-proliferation pattern at 24, 48 and 72 hours exposures. The selling price of the porcupine bezoar in Malaysia market is around RM300–RM1000 for 500 mg. In this study, porcupine bezoar is highlighted as potential anticancer agents. Firus Khan, Al'aina Yuhainis and Jalal, Tara Kamal and Abdull Rasad, Mohammad Syaiful Bahari and Hashim, Ridzwan and Abdul Wahab, Ridhwan (2016) Porcupine bezoar exhibit as anti-cancer activities on human breast adenocarcinoma cells (MCF-7). There are several varieties of bezoar, some of which have inorganic constituents and others organic.The term has both a modern (medical, scientific) and a traditional usage. The bezoar itself is a medical illness (gastrolith) for porcupines and needs to be surgically removed for the porcupine to survive. The chemical profile and the medicinal properties of the bezoar is still unknown. Demand for bezoars isn’t the only threat porcupines face. Alfi Khatib, Google Scholar, Khan FAY, Nasir MMH, Jalal T, Razali S, Hassan H, Asuhaimi FA, Wahab RA (2017) In vitro evaluation of porcupine bezoar extracts as anticancer agent on A549—a preliminary study. The IUCN Red List of Threatened Species. However, its toxicity profile has never been thoroughly investigated to verify its safety nature. PubMed Google Scholar. A porcupine’s diet is wide, varied, and a little hard to digest. Hence, in this study, porcupine bezoar (PB) aqueous extract was evaluated for its potential as a safe anticancer agent. Alfi Khatib, volume 19, pages131–136(2019)Cite this article. Porcupine Bezoar, Klang. JOURNAL OF BIOMEDICAL AND CLINICAL SCIENCES, 1 (Special Issue). A bezoar is a mass found trapped in the gastrointestinal system, though it can occur in other locations. Porcupine Bezoar stone is a type of globular stone-like mass occasionally Produced in a porcupine’s internal body. It was reported as universal medicine in ancient time. Ridhwan Abdul Wahab. Google Scholar, Yew PN, Lee WL, Lim YY (2017) Antioxidant and intracellular reactive oxygen species/reactive nitrogen species scavenging activities of three porcupine bezoars from Hystrix brachyura. 712 likes. Bezoar porcupine benefits in medicine. et al. A traditional folk medicine in Malaysia: porcupine bezoar. Mohammad Syaiful Bahari Abdull Rasad. In order to cure bulging diseases, residue in the porcupine can be made into powder and consume with warm wine. Azir Salleh, Latest issue. This is a preview of subscription content, log in to check access. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. IC50 for DPPH was found to be 0.79 μg/mL ± 0.07. Subscription will auto renew annually. Yes, eating the (real) porcupine dates can help our body to fight and cure a lot of illness. Natural antibodies 3 (2019): Special Issue: Research Towards Sustainable Development Goals, ANTIBACTERIAL EVALUATION OF Curcuma longa, Punica granatum AND Terminalia catappa EXTRACTS, Hystrix brachyura BEZOAR: AN IN VIVO TOXICITY EVALUATION USING EMBRYO ZEBRAFISH (DANIO RERIO) MODEL. The IC50 result for A375 was found to be 10.1 µg/mL ± 0.17. The anti-inflammatory. E-ISSN 2550-147X Porcupine bezoar is undigested concretions of organic or inorganic which calcified and can be found in gastrointestinal tract of porcupine (Malayan hystrix) [7]. A study published recently in the journal Global Ecology and Conservation tracked, for the first time, the online trade in old-world porcupines (those from the family Hystricidae in Asia and Africa). International Islamic University Malaysia, Understanding of Anti-Cancer Properties of Neolamarckia cadamba Leaves Extract on Breast Cancer Cell, INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES: Vol. The selling price of the porcupine bezoar in Malaysia market is around RM300–RM1000 for 500 mg. Ridhwan Abdul Wahab. Porcupine dates are also known as porcupine bezoar, a phytobezoar that is formed from the partly digested plant materials or herbs in the stomach of Himalayan porcupine (Hystrix brachyura) [8, 10]. Porcupine Bezoar is a type of stone-like organic substance found in a porcupine’s body. Porcupine is a mammalian that live in forests. Porcupine bezoar (PB) has been previously reported to possess various medicinal properties. Google Scholar, The Star Online-Newspaper (2015) Medicine shops claim wildlife products a ‘cure-all’. PB aqueous extract showed 11.68 μg/mL ± 0.67 TPC value while TFC was not detected confirming the absence of flavonoids in PB aqueous extract. FIRUS KHAN, A. Y., ABDULLAH ASUHAIMI, F., JALAL, T., NATTO, H. A., ROHEEM, F. O., AHMED, Q. U., JOHAN, M. F., HASHIM, R., & ABDUL WAHAB, R. (2017). Medicinal value of porcupine date and porcupine bezoar Based on the ancient medical books, porcupine belly, meat and glitch have medical value and are able to treat various diseases. It has a coat of sharp spines that defend them from predators. However, its toxicity profile has never been thoroughly ascertained to confirm its safe nature as an efficacious traditional medicine in the treatment of cancer as well as other ailments. Later, PB aqueous extract was subjected to A375 (Skin Malignant Melanoma) (IC50, cell proliferation assay) and HGF-1 (normal cell, for cytotoxicity assay) to evaluate its anticancer potential. The data from this study suggest the potential alternative use of PB in developing natural antioxidants and anti-proliferative agents for improving human health. Ridhwan Abdul Wahab. 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